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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK10
All Species:
16.97
Human Site:
S437
Identified Species:
31.11
UniProt:
P53779
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53779
NP_002744.1
464
52585
S437
S
S
S
V
N
D
I
S
S
M
S
T
D
Q
T
Chimpanzee
Pan troglodytes
Q9N272
365
41989
K339
K
L
T
V
D
E
W
K
Q
H
I
Y
K
E
I
Rhesus Macaque
Macaca mulatta
XP_001094539
426
47882
S400
S
S
V
N
D
I
S
S
M
S
T
D
Q
T
L
Dog
Lupus familis
XP_535641
464
52533
S437
S
S
S
V
N
D
I
S
S
M
S
T
D
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q61831
464
52514
S437
S
S
A
V
N
D
I
S
S
M
S
T
D
Q
T
Rat
Rattus norvegicus
P49187
464
52512
S437
S
S
S
V
N
D
I
S
S
M
S
T
D
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513255
564
63642
P533
N
G
V
V
K
G
Q
P
S
P
S
G
T
R
S
Chicken
Gallus gallus
P79996
382
43990
I356
I
E
E
W
K
E
L
I
Y
K
E
V
M
D
W
Frog
Xenopus laevis
Q8QHK8
426
47910
S400
S
S
S
G
D
A
S
S
M
S
T
D
P
T
L
Zebra Danio
Brachydanio rerio
Q9DGD9
384
44121
K358
E
W
K
E
L
I
Y
K
E
V
L
E
W
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P92208
372
43008
E345
D
H
S
V
D
E
R
E
H
T
V
E
Q
W
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8WQG9
463
52867
D436
L
P
Y
D
H
N
M
D
V
E
Q
N
V
D
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32485
435
48840
V409
D
I
A
G
G
N
K
V
S
D
H
V
A
A
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39
90
99.7
N.A.
98.7
98.7
N.A.
72.3
70.4
79.7
70.2
N.A.
62.7
N.A.
59
N.A.
Protein Similarity:
100
52.5
91.1
99.7
N.A.
98.9
98.9
N.A.
75.5
76.5
84.9
77.1
N.A.
70.9
N.A.
70.9
N.A.
P-Site Identity:
100
6.6
20
100
N.A.
93.3
100
N.A.
20
0
26.6
0
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
33.3
33.3
100
N.A.
100
100
N.A.
40
13.3
40
13.3
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
8
0
0
0
0
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
8
31
31
0
8
0
8
0
16
31
16
0
% D
% Glu:
8
8
8
8
0
24
0
8
8
8
8
16
0
16
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
16
8
8
0
0
0
0
0
8
0
0
0
% G
% His:
0
8
0
0
8
0
0
0
8
8
8
0
0
0
0
% H
% Ile:
8
8
0
0
0
16
31
8
0
0
8
0
0
0
8
% I
% Lys:
8
0
8
0
16
0
8
16
0
8
0
0
8
0
8
% K
% Leu:
8
8
0
0
8
0
8
0
0
0
8
0
0
0
16
% L
% Met:
0
0
0
0
0
0
8
0
16
31
0
0
8
0
0
% M
% Asn:
8
0
0
8
31
16
0
0
0
0
0
8
0
0
8
% N
% Pro:
0
8
0
0
0
0
0
8
0
8
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
8
0
8
0
16
31
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% R
% Ser:
47
47
39
0
0
0
16
47
47
16
39
0
0
0
16
% S
% Thr:
0
0
8
0
0
0
0
0
0
8
16
31
8
16
31
% T
% Val:
0
0
16
54
0
0
0
8
8
8
8
16
8
0
0
% V
% Trp:
0
8
0
8
0
0
8
0
0
0
0
0
8
8
8
% W
% Tyr:
0
0
8
0
0
0
8
0
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _